Study sheds light on immunity transfer from COVID 19 positive mothers
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By: PTI | New Delhi |

December 18, 2020 9:40:05 pm

Here’s what a brand new examine says. (Source: Getty Images/Thinkstock)

Scientists have assessed pregnant sufferers admitted for COVID-19 and located antibodies towards the novel coronavirus in umbilical wire blood, suggesting the opportunity of transferred immunity from moms to infants.

The examine, revealed in The Annals — the official medical journal of the Academy of Medicine, Singapore — periodically analysed samples from 16 pregnant sufferers admitted for COVID-19 to 4 tertiary hospitals in Singapore.

According to the analysis, there was no proof of mother-to-child transmission of the coronavirus by way of breast milk or placenta.
In the examine, the scientists carried out SARS-CoV-2 RT-PCR assessments on maternal blood and vaginal swabs, amniotic fluid and umbilical wire blood (UCB), and swabs of the placental and umbilical wire surfaces.

The researchers, together with these from the Singapore General Hospital, famous that majority of the contaminated pregnant girls had solely delicate illness and solely two of them, who had threat elements like weight problems and older age, had extreme an infection.

None of the ladies died, the examine famous.

Five pregnancies produced time period live-births and two individuals had spontaneous miscarriages at 11 and 23 weeks of being pregnant.
The scientists stated one affected person remained constructive for the SARS-CoV-2 an infection as much as 80 days after preliminary signs however they added that such extended shedding of the virus could not point out precise infectivity.

“Recent reports have highlighted the unpredictable clinical course of COVID-19 infection in pregnancy. Severe maternal disease can manifest prenatally or postnatally and trigger abrupt postnatal decompensation, and its presentation may be delayed up to 14 days from symptom onset,” they wrote within the examine.

However, based mostly on the systematic screening of samples, the scientists stated there was no proof of maternal-child transmission of the virus.

The researchers additionally discovered SARS-CoV-2-specific antibodies within the paired maternal and umbilical wire blood.

But they stated this discovering might not be conclusive proof of the switch of antibodies from moms to infants for the reason that protecting proteins may be trafficked in instances the place the maternal-fetal interface is breached by irritation.

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